Benefits of Synexus model

Speeds up clinical trials

Phase II

Synexus can dramatically reduce the timelines of a Phase II trial where the entire trial is conducted at one or more of Synexus' Dedicated Research Centres simply because there is no investigator enrollment, there is only one contract covering the trial and Synexus streamlines the processes from start to finish.

Phase III or IV

Whilst Synexus can radically reduce the time involved in investigator and patient recruitment, the length of the trial will still be determined by when the last site finishes enrolling patients. However, Synexus is often asked to find more patients and this can usually be achieved without lengthening the duration of the trial because of the considerable capacity Synexus has across its Dedicated Research Centres and its ability to put in place highly effective patient recruitment campaigns at short notice.

Reduces the cost of clinical trials

• Phase II

Synexus significantly reduces the cost of running a Phase II study where the entire trial is carried out at one or more of Synexus' Dedicated Research centres because:

• There is no investigator enrollment
• One contract rather than many (average cost of single investigator enrollment and contract is $30,000)
• There is one, or at most three sites to monitor.

Case Studies

• Phase III

Synexus' ability to enrol thousands of patients efficiently and quickly reduces the costs in Phase III by:

• Substantially reducing the number of investigators to be recruited.
• Reducing the number of contracts to be negotiated - Synexus has one contract regardless of the number of Dedicated Research Centres involved.
• Reducing the number of sites to be monitored.

Case Studies

Provides access to millions of patients worldwide

• Synexus has access to millions of patients through its network of 26 Dedicated Research Centres in the UK, Germany, Austria, Poland, Hungary, Bulgaria, Ukraine, South Africa and India
• Patient populations are varied including treatment naive patients.

Provides cleaner data

• Every data entry made by a Synexus investigator is double-checked by a data entry specialist to ensure fewer queries.

Provides the same high standards in every Synexus Centre worldwide

• All staff are GCP trained and operate to the same SOPs across the world

• A strict quality control team ensures that every Dedicated Research Centre adheres to the SOPs
• Synexus investigators are full-time experts in conducting clinical trials.